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Dx Fecal Calprotectin IVD ELISA kit

Catalog #: DH002

Quantity: 1 x 96 det.

Calprotectin, also known as S100A8/A9 heterocomplex, is formed out of the calcium-binding, migrating proteins S100A8 and S100A9. Calprotectin is a calcium- and zinc-binding protein complex composed of 8 and 14 kD subunits and complex formation is calcium dependent. Neutrophils are the main producers of calprotectin, but expression has also been found in monocytes, macrophages and ileal tissue eosinophils. Altogether, S100A8 and S100A9 proteins contribute to approximately 40–60% of the soluble, cytosolic content of granulocytes. Calprotectin has antibacterial, antifungal, immunomodulating and antiproliferative effects. Elevated concentrations of calprotectin can be measured among others in plasma, synovial fluid, urine and feces. The presence of calprotectin in feces quantitatively relates to neutrophil migration towards the gastrointestinal tract.n

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Availability: In stock

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