5-Hydroxymethylcytosine/ 5-hmC Rabbit pAb - A20140
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Catalog #
AB-A20140
Ab
100,00 €
In mammalian genomes, 5-mC can be enzymatically oxidized to 5-hmC (5-hydroxymethylcytosine). This modification is suggested to be an intermediate between methylation and demethylation of the genome. Occupancy of 5-hmC correlates with inactive or non-productive promoters (PMID: 21925312). 5-hmC pattern is different from 5-methylcytosine (5-mC) in many instances(PMID: 21610077).
| Isotype | IgG |
|---|---|
| Datasheet URL | https://abclonal.com/instructions/pdf/A20140 |
| Alternative Names | 5-hmC; 5hmc; 5-HydroxyMethyl cytidine; hm5c; 5-Hydroxymethylcytosine/ 5-hmC |
| Source | Rabbit |
| Purity | Affinity purification |
| Immunogen | Chemical compounds corresponding to 5-hydroxymethylcytidine / hm5C. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |