Recombinant Human R-spondin-1/RSPO1 Protein - RP00071
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Catalog #
AB-RP00071
This protein is a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP00071 |
|---|---|
| Alternative Names | RSPO1,CRISTIN3,RSPO |
| Species | Human |
| Source | HEK293 cells |
| Purity | >95%bySDS-PAGE. |
| Immunogen | Arg31-Ala263 |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |