Recombinant Human PDGFR-beta/CD140b(E241D) Protein - RP00126
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Catalog #
AB-RP00126
Ab
65,00 €
The protein is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP00126 |
|---|---|
| Alternative Names | CD140B,IBGC4,IMF1,JTK12,KOGS,PDGFR,PDGFR-1,PDGFR1,PENTT,PDGF Receptor beta,PDGFRB,PDGFR beta |
| Species | Human |
| Source | HEK293 cells |
| Purity | >90%bySDS-PAGE. |
| Immunogen | Leu33-Phe530(E241D) |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |