Recombinant Human Cathepsin D Protein - RP00214
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Catalog #
AB-RP00214
Ab
110,00 €
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family. It is expressed in most cells and overexpressed in breast cancer cells. It is a major enzyme in protein degradation in lysosomes, and also involved in the presentation of antigenic peptides. cathepsin D is essential for proteolysis of proteins regulating cell growth and tissue homeostasis. CTSD secreted from human prostate carcinoma cells are responsible for the generation of angiostatin, a potent endogenous inhibitor of angiogenesis, suggesting its contribution to the prevention of tumor growth and angiogenesis-dependent growth of metastases.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP00214 |
|---|---|
| Alternative Names | CLN10,CPSD,HEL-S-130P,Cathepsin D,CTSD |
| Species | Human |
| Source | HEK293 cells |
| Purity | >95%bySDS-PAGE. |
| Immunogen | Leu21-Leu412 |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |