Recombinant Mouse TNFSF4/OX40 ligand/CD252 Protein - RP00713
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Catalog #
AB-RP00713
Ab
115,00 €
OX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptorsuperfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival andfor the generation of memory T cells from activated effector T cells. OX40L – OX40 co-stimulation leads toactivation of TNF receptor associated factor (TRAF) 2, 3 and 5. This pathway has been shown to prolong thesurvival of effector CD4+Th cells as well as contributes to generation of memory T cells.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP00713 |
|---|---|
| Alternative Names | Tumor necrosis factor ligand superfamily member 4, TNFSF4, CD134 ligand, CD134L, CD252,CD252 antigen, OX40 antigen ligand, OX40 ligand, OX40L, TAX transcriptionally-activatedglycoprotein 1, tumor necrosis factor (ligand) superfamily, member 4, Tnfsf4 |
| Species | MOUSE |
| Source | HEK293 cells |
| Purity | >95%bySDS-PAGE. |
| Immunogen | Ser51-Leu198 |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |