Recombinant Human TNFSF12/TWEAK Protein - RP01446
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Catalog #
AB-RP01446
Ab
81,00 €
Regular Price
90,00 €
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP01446 |
|---|---|
| Alternative Names | TNFSF12,APO3L,DR3LG,TNLG4A,TWEAK |
| Species | Human |
| Source | E. coli |
| Purity | >95%bySDS-PAGE. |
| Immunogen | Lys97-His249（N-Met) |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |