In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1) - YR0292
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Catalog #
AB-YR0292
Ab
292,00 €
The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mouse PD-1 protein (CD279 or programmed death-1) encoded by the mouse pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD 1 antibody and the anti-mouse PD L1 antibody which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The RMP1-14 antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein.
| Isotype | Rat IgG2a kappa |
|---|---|
| Datasheet URL | https://abclonal.com/instructions/pdf/YR0292 |
| Species | RMP1 14.1 |
| Source | 0.2 μm filtration |
| Purity | >95% Determined by SDS-PAGE |
| Immunogen | mouse PD-1-transfected BHK cells |
| Storage | 2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing) |
| Conjugate | <5%DeterminedbySECP |