Anti-inflammatory agent 75 - HY-N12615

Anti-inflammatory agent 75 (Compound 14) is an α-pyrone derivative that can be isolated from the traditional medicinal plant St. John's Wort (Hypericum henryi.). Anti-inflammatory agent 75 has anti-inflammatory activity, inhibiting the phosphorylation and degradation of NF-κB inhibitors, thereby suppressing the activation of NF-κB[1].