Basophils, Human, mAb 2D7 – 100 µg - HM2279-100UG
Quantity
100 µg
Catalog #
HM2279-100UG
368,00 €
Unlock the secrets of immune response with our precision-targeted 2D7 monoclonal antibody, the definitive marker for basophils. This innovative tool zeroes in on a unique 7.2-7.5 kDa protein exclusive to basophil secretory granules, enabling researchers to track basophil activation with unparalleled clarity. As gatekeepers of inflammatory and allergic reactions, basophils are pivotal in the release of histamine and cytokines, and in prompting B cells to produce IgE. Originating in the bone marrow, these critical cells circulate in the bloodstream, ready to converge at inflammation sites. With the 2D7 antibody, detect the subtle interplay of basophils in allergic conditions with exacting specificity—excluding interference from lymphocytes, monocytes, eosinophils, neutrophils, and mast cells. Elevate your research with the precision of 2D7 antibody in immunohistochemistry and western blot applications, and illuminate the role of basophils in human health and disease.
| Datasheet URL | https://www.hycultbiotech.com/wp-content/uploads/2022/06/coa-tds_hm2279-20ug.pdf |
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| Quantity | 100ug |
| Quantity | 100 µg |
| Species | human |
| Application | Flow cytometry, Frozen sections, Immuno fluorescence, Paraffin sections, Western blot |
| Precautions | For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result from the use or derivation of this product. |
| References | 1. Kepley, C et al; Identification and partial characterization of a unique marker for human basophils. J Immunol 1995, 154: 6548. 2. Irani, A et al; Immunohistochemical detection of human basophils in late-phase skin reactions. J Allergy Clin Immunol 1998, 101: 354. 3. Agis, H et al; Enumeration and immunohistochemical characterisation of bone marrow basophils in myeloproliferative disorders using the basophil specific monoclonal antibody 2D7. J Clin Pathol 2006, 59: 396 4. Plager, D et al; Identification of basophils by a mAb directed against pro-major basic protein 1. J Allergy Clin Immunol 2006, 117: 626 |
| Disease | Infectious diseases |
| Application: | Flow cytometry Frozen sections Immuno fluorescence Paraffin sections Western blot |
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