Biotinylated Recombinant Human P53 WT (HLA-A*02:01) Complex Protein - RP02756
Catalog #
AB-RP02756
820,00 €
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
| Datasheet URL | https://abclonal.com/instructions/pdf/RP02756 |
|---|---|
| Quantity | 100ug |
| Alternative Names | MHC; HLA-A; P53; TP53; Antigen NY-CO-13; BCC7; FLJ92943; LFS1; TRP53 |
| Species | Human |
| Source | HEK293 cells |
| Purity | >95%asdeterminedbyTris-BisPAGE；>95%asdeterminedbyHPLC |
| Immunogen | Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and HMTEVVRRC peptide |
| Storage | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |