C3, Mouse, pAb – 100 µg - HP8012-100UG
Quantity
100 µg
Catalog #
HP8012-100UG
456,00 €
Verwandte Produkte
The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha-chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
| Datasheet URL | https://www.hycultbiotech.com/wp-content/uploads/2022/06/coa-tds_hp8012-20ug.pdf |
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| Quantity | 100ug |
| Quantity | 100 µg |
| Species | MOUSE |
| Alias | Complement component C3, HSE-MSF Gene name: C3 |
| Application | Frozen sections, Immuno fluorescence, Paraffin sections, Western blot |
| Precautions | For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product. |
| References | 1. Cashman, S et al; Expression of complement component 3 (C3) from an adenovirus leads to pathology in the murine retina. Inv Opht Vis Scie 2011, 52: 3436 2. Bengtson, A et al; Pharmacokinetics, Tolerability, and Preliminary Efficacy of Paquinimod (ABR-215757), a New Quinoline-3-Carboxamide Derivative: studies in lupus-prone mice and a multicenter, randomized, double-blind, placebo-controlled, repeat-dose, dose-ranging study in patients with systemic lupus erythematosus. Arthritis Rheum 2012, 64: 1579 3. Tati, R et al. Complement activation associated with ADAMSTS13 deficiency in human and murine thrombotic microangiopathy. JI 2013, 191:2184 |
| Disease | Infectious diseases, Nephrology |
| Application: | Frozen sections Immuno fluorescence Paraffin sections Western blot |
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