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ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure VDR antagonist with a Kd value of 0.1 nM. ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor.
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Menge 1 mg
CAS 186371-96-0
MWT 510.7
Formula C32H46O5
Clinical Information No Development Reported
Pathway Vitamin D Related
Target VD/VDR