CBR-5884 - HY-100012
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Catalog #
HY-100012
Ab
82,00 €
CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-100012/CBR-5884-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 681159-27-3 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 336.39 |
| Solubility | DMSO : 50 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Phosphoglycerate Dehydrogenase (PHGDH) |
| Application: | Cancer-programmed cell death |
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