MK-4101 - HY-100036

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Catalog #
HY-100036
Ab 26,00 €
MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells; IC50 of 1 μM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis[1].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-100036/MK-4101-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-programmed cell death
CAS 935273-79-3
Storage -20°C, 3 years; 4°C, 2 years (Powder)
MWT 493.47
Solubility DMSO : ≥ 50 mg/mL
Clinical Information No Development Reported
Target Apoptosis;Hedgehog;Smo
Applications
Application: Cancer-programmed cell death

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