Semagacestat - HY-10009
Nur noch %1 verfügbar
Catalog #
HY-10009
Ab
58,00 €
Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid (Aβ42), Aβ38 and Aβ40 with IC50s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's disease[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-10009/Semagacestat-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Application | Neuroscience-Neurodegeneration |
| Alternative Names | LY450139 |
| CAS | 425386-60-3 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 361.44 |
| Solubility | DMSO : ≥ 100 mg/mL |
| Clinical Information | Phase 3 |
| Target | Amyloid-β;Notch;γ-secretase |
| Application: | Neuroscience-Neurodegeneration |
|---|