SHP099 - HY-100388
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Catalog #
HY-100388
Ab
72,00 €
SHP099 is an allosteric SHP2 inhibitor, with IC50s of 0.690, 1.241, 0.416, 1.968, 2.896 μM for SHP2, SHP2D61Y, SHP2E69K, SHP2A72V, SHP2E76K. SHP099 inhibits cancer cell growth, such as MV4-11 and TF-1 cell (IC50: 0.32 and 1.73 μM). SHP099 inhibits RAS-ERK signaling and inhibits tumor growth[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-100388/SHP099-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| CAS | 1801747-42-1 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 352.26 |
| Solubility | DMSO : 12 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Phosphatase;SHP2 |
| Application: | Cancer-Kinase/protease |
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