CPI-455 - HY-100421
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Catalog #
HY-100421
Ab
45,00 €
CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-100421/CPI-455-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 1628208-23-0 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 278.31 |
| Solubility | DMSO : 31.25 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Histone Demethylase |
| Application: | Cancer-programmed cell death |
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