NCB-0846 - HY-100830

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Catalog #
HY-100830
Ab 93,00 €
NCB-0846 is an orally active, selective inhibitor for Wnt, that inhibits Traf2- and Nck-interacting kinase (TNIK) with an IC50 of 21 nM. NCB-0846 blocks TGF-β signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation[1][2].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-100830/NCB-0846-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-Kinase/protease
CAS 1792999-26-8
Storage -20°C, 3 years; 4°C, 2 years (Powder)
MWT 375.42
Solubility DMSO : ≥ 30 mg/mL
Clinical Information No Development Reported
Target MAP4K;TGF-beta/Smad;Wnt
Applications
Application: Cancer-Kinase/protease

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