GSK-872 - HY-101872
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Catalog #
HY-101872
Ab
43,00 €
GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury[1][2][3].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-101872/GSK-872-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | COVID-19-immunoregulation |
| CAS | 1346546-69-7 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 383.49 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | RIP kinase |
| Application: | COVID-19-immunoregulation |
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