Masitinib - HY-10209
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Catalog #
HY-10209
Ab
39,00 €
Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity[1][2][4].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-10209/Masitinib-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| Alternative Names | AB1010 |
| CAS | 790299-79-5 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 498.64 |
| Solubility | DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL |
| Clinical Information | Launched |
| Target | Apoptosis;c-Kit;FAK;FGFR;PDGFR;Src |
| Application: | Cancer-Kinase/protease |
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