Rapamycin - HY-10219

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Catalog #
HY-10219
Ab 33,00 €
Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-10219/Rapamycin-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-Kinase/protease
Alternative Names Sirolimus; AY-22989; NSC 226080
CAS 53123-88-9
Storage -20°C, 3 years; 4°C, 2 years (Powder)
MWT 914.17
Solubility DMSO : 100 mg/mL (ultrasonic)
Clinical Information Launched
Target Antibiotic;Autophagy;Bacterial;Endogenous Metabolite;FKBP;Fungal;mTOR
Applications
Application: Cancer-Kinase/protease

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