Fasudil (Hydrochloride) - HY-10341
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Catalog #
HY-10341
Ab
87,00 €
Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-10341/Fasudil-Hydrochloride-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| Alternative Names | HA-1077 (Hydrochloride); AT-877 (Hydrochloride) |
| CAS | 105628-07-7 |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| MWT | 327.83 |
| Solubility | DMSO : ≥ 31 mg/mL|H2O : 55 mg/mL (ultrasonic) |
| Clinical Information | Launched |
| Target | Autophagy;Calcium Channel;HIV;PKA;PKC;ROCK |
| Application: | Cancer-Kinase/protease |
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