PROTAC Sirt2 Degrader-1 - HY-103636

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Catalog #
HY-103636
Ab 465,00 €
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM)[1].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-103636/PROTAC-Sirt2-Degrader-1-DataSheet-MedChemExpress.pdf
Shipping Blue Ice
Application Cancer-programmed cell death
CAS 2098487-75-1
Storage -20°C, 3 years (Powder)
MWT 852.94
Solubility DMSO : ≥ 100 mg/mL
Clinical Information No Development Reported
Target PROTACs;Sirtuin
Applications
Application: Cancer-programmed cell death

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