Gedatolisib - HY-10681
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Catalog #
HY-10681
Ab
43,00 €
Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively[1]. Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2[2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-10681/Gedatolisib-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| Alternative Names | PKI-587; PF-05212384 |
| CAS | 1197160-78-3 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 615.73 |
| Solubility | DMSO : 4 mg/mL (warming)|H2O : < 0.1 mg/mL |
| Clinical Information | Phase 3 |
| Target | mTOR;PI3K |
| Application: | Cancer-Kinase/protease |
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