Tolebrutinib - HY-109192
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Catalog #
HY-109192
Ab
88,00 €
Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS)[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-109192/Tolebrutinib-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| Alternative Names | SAR442168; PRN2246 |
| CAS | 1971920-73-6 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 455.51 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | Phase 3 |
| Target | Btk |
| Application: | Cancer-Kinase/protease |
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