IACS-010759 (hydrochloride) - HY-112037A

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Catalog #
HY-112037A
Ab 155,00 €
IACS-010759 hydrochlorideis an orally active, potent mitochondrial complex I of oxidative phosphorylation (OXPHOS) inhibitor. IACS-010759 hydrochlorideinhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML) reliant on OXPHOS. IACS-010759 hydrochloride has the potential for relapsed/refractory AML and solid tumors research[1][2].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-112037A/IACS-010759-hydrochloride-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-Kinase/protease
Alternative Names IACS-10759 (hydrochloride)
CAS 1807523-99-4
Storage 4°C (Powder, sealed storage, away from moisture)
MWT 599.02
Solubility DMSO : 60 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Clinical Information Phase 1
Target Apoptosis;Mitochondrial Metabolism;Oxidative Phosphorylation
Applications
Application: Cancer-Kinase/protease

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