C188-9 - HY-112288
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Catalog #
HY-112288
Ab
114,00 €
C188-9 (TTI-101) is a STAT3 inhibitor, with a Kd of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts[1][2][3][4].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-112288/C188-9-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| Alternative Names | TTI-101 |
| CAS | 432001-19-9 |
| Storage | 4°C (Powder, protect from light) |
| MWT | 471.52 |
| Solubility | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
| Clinical Information | Phase 2 |
| Target | Apoptosis;STAT |
| Application: | Cancer-Kinase/protease |
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