PROTAC TBK1 degrader-2 - HY-112557

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Catalog #
HY-112557
Ab 356,00 €
PROTAC TBK1 degrader-2 is a Ligands for Target Protein for PROTAC. PROTAC TBK1 degrader-2 is a potent degrader based on the serine/threonine kinase TANK-binding kinase 1 (TBK1) (DC50=15 nM; Kd=4.6 nM) with a maximum efficiency of 96%. PROTAC TBK1 degrader-2 also targets to IkB kinase IKKε (IC50=8.7 nM), with low selectivity over TBK1 (IC50=1.3 nM)[1].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-112557/PROTAC-TBK1-degrader-2-DataSheet-MedChemExpress.pdf
Shipping Blue Ice
Application Cancer-Kinase/protease
CAS 2052306-13-3
Storage -20°C, 3 years (Powder)
MWT 1093.18
Solubility DMSO : 110 mg/mL (ultrasonic;warming)
Clinical Information No Development Reported
Target IKK;PROTACs
Applications
Application: Cancer-Kinase/protease

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