Sappanone A - HY-113556

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Catalog #
HY-113556
Ab 72,00 €
Sappanone A is an orally active homoisoflavone found in sappan L. Sappanone A is a PDE4 and NF-κB inhibitor with anti-inflammatory and antioxidant effect. Sappanone A induces HO-1 expression through activation of Nrf2 pathway. Sappanone A also inhibits RANKL-induced osteoclastogenesis. Sappanone A has great potential in the research of inflammation-related and cardiovascular
[1][2][3][4][5].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-113556/Sappanone-A-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application COVID-19-immunoregulation
CAS 102067-84-5
Storage 4°C (Powder, protect from light)
MWT 284.26
Solubility DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Clinical Information No Development Reported
Target Akt;COX;ERK;Interleukin Related;JNK;Keap1-Nrf2;NF-κB;NO Synthase;Nuclear Factor of activated T Cells (NFAT);p38 MAPK;Phosphodiesterase (PDE);Reactive Oxygen Species (ROS);TNF Receptor
Applications
Application: COVID-19-immunoregulation

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