PLX5622 - HY-114153
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Catalog #
HY-114153
Ab
107,00 €
PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 μM; Ki=5.9 nM). PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-114153/PLX5622-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Neuroscience-Neuromodulation |
| CAS | 1303420-67-8 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 395.41 |
| Solubility | DMSO : 50 mg/mL (ultrasonic)|Ethanol : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL |
| Clinical Information | Phase 1 |
| Target | c-Fms |
| Application: | Neuroscience-Neuromodulation |
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