JR-AB2-011 - HY-122022
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Catalog #
HY-122022
Ab
269,00 €
JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. JR-AB2-011 inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM)[1].JR-AB2-011 decreases the phosphorylation level of Akt, decreases MMP2 activity, thereby reducing the ability of tumor cells to migrate and invade. JR-AB2-011 also induces non-apoptotic cell death[2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-122022/JR-AB2-011-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-Kinase/protease |
| CAS | 2411853-34-2 |
| Storage | 4°C (Powder, protect from light) |
| MWT | 398.28 |
| Solubility | DMSO : 62.5 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | mTOR |
| Application: | Cancer-Kinase/protease |
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