JNJ-55308942 - HY-123857
Nur noch %1 verfügbar
Catalog #
HY-123857
Ab
217,00 €
JNJ-55308942 is a high-affinity, selective, brain-penetrant P2X7 functional antagonist (hP2X7: IC50=10 nM, Ki=7.1 nM; rP2X7: IC50=15 nM, Ki=2.9 nM). JNJ-55308942 is orally bioavailable, binds to brain P2X7 and blocks IL-1β release from adult rodent brain[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-123857/JNJ-55308942-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Application | COVID-19-immunoregulation |
| CAS | 2166558-11-6 |
| Storage | 4°C (Powder, sealed storage, away from moisture and light) |
| MWT | 425.32 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | Phase 2 |
| Target | P2X Receptor |
| Application: | COVID-19-immunoregulation |
|---|