TED-347 - HY-125269
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Catalog #
HY-125269
Ab
114,00 €
TED-347 is a potent, irreversible, covalent and allosteric inhibitor at YAP-TEAD protein-protein interaction with an EC50 of 5.9 μM for TEAD4 Yap1 protein-protein interaction. TED-347 specifically and covalently bonds with Cys-367 within the central pocket of TEAD4 with a Ki of 10.3 μM. TED-347 blocks TEAD transcriptional activity and has antitumor activity[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-125269/TED-347-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 2378626-29-8 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 313.70 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | YAP |
| Application: | Cancer-programmed cell death |
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