Prucalopride (succinate) - HY-12694
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Catalog #
HY-12694
Ab
35,00 €
Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer[1][2][3][4].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-12694/Prucalopride-succinate-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Alternative Names | R-108512 |
| CAS | 179474-85-2 |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| MWT | 485.96 |
| Solubility | DMSO : 50 mg/mL (ultrasonic)|H2O : ≥ 20 mg/mL |
| Clinical Information | Launched |
| Target | 5-HT Receptor;Apoptosis;Autophagy |