PROTAC CRBN Degrader-1 - HY-128845
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Catalog #
HY-128845
Ab
153,00 €
PROTAC CRBN Degrader-1 (Compound 14a) is a VHL-CRBN heterodimerization PROTAC degrader that achieves a selective degradation of CRBN by binding two E3 ubiquitin ligases (VHL and CRBN) to each other[1]. (Blue: VHL ligand (S,R,S)-AHPC (HY-125845); Pink: CRBN ligand Pomalidomide-C2-NH2 (HY-128846); Black: Linker (HY-128847))
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-128845/PROTAC-CRBN-Degrader-1-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 2358775-70-7 |
| Storage | 4°C (Powder, stored under nitrogen) |
| MWT | 1061.25 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | E1/E2/E3 Enzyme;PROTACs |
| Application: | Cancer-programmed cell death |
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