PROTAC CDK2/9 Degrader-1 - HY-130709

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Catalog #
HY-130709
Ab 775,00 €
PROTAC CDK2/9 Degrader-1 (Compound F3) is a potent dual degrader for CDK2 (DC50=62 nM) and CDK9 (DC50=33 nM). PROTAC CDK2/9 Degrader-1 suppresses prostate cancer PC-3 cell proliferation (IC50=0.12 µM) by effectively blocking the cell cycle in S and G2/M phases. PROTAC CDK2/9 Degrader-1 is a PROTAC by tethering CDK inhibitor with Cereblon ligand[1].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-130709/PROTAC-CDK2-9-Degrader-1-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-Kinase/protease
CAS 2408641-24-5
Storage -20°C, 3 years; 4°C, 2 years (Powder)
MWT 815.84
Solubility DMSO : 50 mg/mL (ultrasonic)
Clinical Information No Development Reported
Target CDK;PROTACs
Applications
Application: Cancer-Kinase/protease

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