PROTAC IDO1 Degrader-1 - HY-131911
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Catalog #
HY-131911
Ab
351,00 €
PROTAC IDO1 Degrader-1 is the first potent IDO1 (indoleamine 2,3-dioxygenase 1) degrader that hijacks IDO1 to Cereblon E3 ligase to introduce IDO1 into UPS and eventually achieve ubiquitination and degradation (DC50=2.84 μM). PROTAC IDO1 Degrader-1 moderately improves the tumor-killing activity of H ER2 CAR-T cells[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-131911/PROTAC-IDO1-Degrader-1-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | COVID-19-immunoregulation |
| CAS | 2488851-89-2 |
| Storage | -20°C (Powder, sealed storage, away from moisture) |
| MWT | 966.80 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Indoleamine 2,3-Dioxygenase (IDO);PROTACs |
| Application: | COVID-19-immunoregulation |
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