Belnacasan - HY-13205
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Catalog #
HY-13205
Ab
57,00 €
Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-13205/Belnacasan-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | COVID-19-immunoregulation |
| Alternative Names | VX-765 |
| CAS | 273404-37-8 |
| Storage | -20°C, 3 years (Powder) |
| MWT | 509.00 |
| Solubility | DMSO : 100 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C) |
| Clinical Information | Phase 2 |
| Target | Caspase |
| Application: | COVID-19-immunoregulation |
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