DB1976 (dihydrochloride) - HY-135797A
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Catalog #
HY-135797A
Ab
393,00 €
DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect[1][2][3].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-135797A/DB1976-dihydrochloride-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 2369663-93-2 |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| MWT | 520.28 |
| Solubility | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 18.33 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Apoptosis |
| Application: | Cancer-programmed cell death |
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