ARN-21934 - HY-137466
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Catalog #
HY-137466
Ab
289,00 €
ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-137466/ARN-21934-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | Cancer-programmed cell death |
| CAS | 2230854-93-8 |
| Storage | -20°C, 3 years (Powder) |
| MWT | 360.46 |
| Solubility | DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 80°C) |
| Clinical Information | No Development Reported |
| Target | Topoisomerase |
| Application: | Cancer-programmed cell death |
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