GNE-987 GSH linker-2 - HY-138634
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Catalog #
HY-138634
Ab
517,00 €
GNE-987 GSH linker-2 (compound 9a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GNE-987 GSH linker-2 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-138634/GNE-987-GSH-linker-2-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | Cancer-programmed cell death |
| Storage | -20°C (Powder, sealed storage, away from moisture and light) |
| MWT | 1292.56 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Epigenetic Reader Domain;PROTAC-Linker Conjugates for PAC |
| Application: | Cancer-programmed cell death |
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