AES-350 - HY-138831

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Catalog #
HY-138831
Ab 330,00 €
AES-350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 is also against HDAC3, HDAC8 in an enzymatic activity assay with IC50 values of 0.187 μM and 0.245 μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research[1].
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-138831/AES-350-DataSheet-MedChemExpress.pdf
Shipping Room Temperature
Application Cancer-programmed cell death
CAS 847249-57-4
Storage 4°C (Powder, protect from light)
MWT 312.36
Solubility DMSO : 100 mg/mL (ultrasonic)
Clinical Information No Development Reported
Target Apoptosis;HDAC
Applications
Application: Cancer-programmed cell death

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