Prucalopride - HY-14151
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Catalog #
HY-14151
Ab
35,00 €
Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer[1][2][3].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-14151/Prucalopride-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Neuroscience-Neuromodulation |
| CAS | 179474-81-8 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 367.87 |
| Solubility | DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic) |
| Clinical Information | Launched |
| Target | 5-HT Receptor;Apoptosis;Autophagy |
| Application: | Neuroscience-Neuromodulation |
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