MK-886 - HY-14166
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Catalog #
HY-14166
Ab
39,00 €
MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis[1][2][3].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-14166/MK-886-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| Alternative Names | L 663536 |
| CAS | 118414-82-7 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 472.08 |
| Solubility | DMSO : 75 mg/mL (ultrasonic) |
| Clinical Information | Phase 2 |
| Target | Apoptosis;FLAP;Leukotriene Receptor;PPAR |
| Application: | Cancer-programmed cell death |
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