Casopitant (mesylate) - HY-14405A
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Catalog #
HY-14405A
Ab
413,00 €
Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV)[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-14405A/Casopitant-mesylate-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Neuroscience-Neuromodulation |
| Alternative Names | GW679769B |
| CAS | 414910-30-8 |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| MWT | 712.72 |
| Solubility | DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C) |
| Clinical Information | Phase 3 |
| Target | Cytochrome P450;Neurokinin Receptor |
| Application: | Neuroscience-Neuromodulation |
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