Plinabulin - HY-14444
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Catalog #
HY-14444
Ab
98,00 €
Plinabulin (NPI-2358) is a vascular disrupting agen (VDA) against tubulin-depolymerizing with an IC50 of 9.8 nM against HT-29 cells[1]. Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells[2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-14444/Plinabulin-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| Alternative Names | NPI-2358 |
| CAS | 714272-27-2 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 336.39 |
| Solubility | DMSO : 50 mg/mL (ultrasonic) |
| Clinical Information | Phase 3 |
| Target | Microtubule/Tubulin |
| Application: | Cancer-programmed cell death |
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