Retinoic acid - HY-14649

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Catalog #
HY-14649
Ab 62,00 €
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
Weitere Informationen
Datasheet URL http://file.medchemexpress.com/batch_PDF/HY-14649/Retinoic-acid-DataSheet-MedChemExpress.pdf
Shipping Blue Ice
Application Cancer-programmed cell death
Alternative Names Vitamin A acid; all-trans-Retinoic acid; ATRA
CAS 302-79-4
Storage -20°C (Powder, sealed storage, away from moisture and light)
MWT 300.44
Solubility DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Clinical Information Launched
Target Autophagy;Endogenous Metabolite;Organoid;PPAR;RAR/RXR
Applications
Application: Cancer-programmed cell death

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