Retinoic acid-d5 - HY-14649S4
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Catalog #
HY-14649S4
Ab
496,00 €
Retinoic acid-d5 is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2][3][4][5].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-14649S4/Retinoic-acid-d5-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Alternative Names | Vitamin A acid-d5; all-trans-Retinoic acid-d5; ATRA-d5 |
| CAS | 78996-15-3 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 305.47 |
| Solubility | 10 mM in DMSO|DMSO : 50mg/mL (ultrasonic;warming;heat to 60°C) |
| Clinical Information | No Development Reported |
| Target | Autophagy;Endogenous Metabolite;Isotope-Labeled Compounds;PPAR;RAR/RXR |