PROTAC EGFR degrader 7 (diTFA) - HY-147858A
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Catalog #
HY-147858A
Ab
775,00 €
PROTAC EGFR degrader 7 (compound 13b) is a potent and selective CRBN-recruiting PROTAC EGFRL858R/T790M degrader, with a DC50 of 13[1].2 nM.PROTAC EGFR degrader 7 inhibits NCI-H1975 cells proliferation, with an IC50 of 46[1].82 nM.PROTAC EGFR degrader 7 significantly induces apoptosis and G2/M phase arrest in NCI-H1975 cell.PROTAC EGFR degrader 7 shows antitumor activity, and can be used for non-small cell lung cancer (NSCLC) research[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-147858A/PROTAC-EGFR-degrader-7-diTFA-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | Cancer-programmed cell death |
| Storage | -20°C (Powder, sealed storage, away from moisture and light) |
| MWT | 1064.98 |
| Solubility | DMSO : 100 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | PROTACs |
| Application: | Cancer-programmed cell death |
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